The NanoRam-1064 is a state-of-the-art handheld Raman instrument for nondestructive identification and verification of incoming raw materials such as APIs, excipients, and intermediates. Compact and agile, the NanoRam can be used by non-technical users to rapidly identify samples in the lab, warehouse, loading dock or field, helping to eliminate quarantine areas and expedite materials through the manufacturing lifecycle. Utilizing Raman technology, analysis can be performed through transparent containers, all while maintaining the volume and integrity of the sample. The high-performance NanoRam-1064 minimizes fluorescence, and can differentiate different grades of cellulose, polysorbate and Opadry®.

The NIRS DS2500 Analyzer is the tried and tested, flexible solution for routine analysis of solids, creams, and optionally also liquids along the entire production chain. Its robust design makes the NIRS DS2500 Analyzer resistant to dust, moisture, vibrations, and temperature fluctuations, which means that it is eminently suited for use in harsh production environments. The NIRS DS2500 covers the full spectral range from 400 to 2500 nm and delivers accurate, reproducible results in under a minute. The NIRS DS2500 Analyzer meets the demands of the pharmaceutical industry and supports users in their day-to-day tasks thanks to its simple operation.

The NIRS XDS Interactance OptiProbe Analyzer enables the simple and reliable monitoring of chemical reactions in technical centers and pilot plants. The method development and the scale-up of production processes are areas of application in which the NIRS XDS Interactance OptiProbe Analyzer supplies precise results regarding the identity and quality of a wide variety of samples. Whereas solids, strongly scattering liquids and slurries are measured with the reflection probe, the immersion probe is used to analyze aqueous products, clear liquids and solvents. The probe is connected to the analyzer through an optical fiber to enable secure measurements even under rough and/or dangerous conditions in the processing environment.

The NIRS XDS MasterLab Analyzer enables the rapid, nondestructive analyses of solid-state dosage forms such as tablets, capsules, film-coated tablets, gel tablets and gel capsules for manufacturers in the pharmaceuticals industry. Solids in vials can also be analyzed with the NIRS XDS MasterLab Analyzer. The analysis takes place in reflection or transmission mode. The sample input proceeds via a sample slide that can be moved in x and y direction and that is designed for trays with several tablets and/or vials. Analyses of individual samples are optimized with an iris. An optionally available coarse granular sample cell for coarse granular substances extends analysis to include practically all solid forms ranging from fine powders to coarse granular materials, e.g., pellets and flakes

The NIRS XDS RapidContent Analyzer enables rapid, nondestructive analyses of solid powders, coarser granulates, pellets or flakes. Composition or material identification testing is performed either in the laboratory or at-line, on samples contained in their original packaging, bags or vials. An optional variable spot-size feature enables the sample illumination to be adjusted based on the physical properties of your samples.

The NIRS XDS RapidLiquid Analyzer enables rapid, precise analyses of liquid formulations and substances. Precise measurement results at the push of a button make the NIRS XDS RapidLiquid Analyzer an equally reliable and simple solution for quality monitoring in laboratories and processes. The samples are transferred to quartz cuvettes designed for multiple use or disposable glass vials; a tempered sample compartment ensures reproducible analysis conditions and thus accurate measurement results

The NIRS XDS SmartProbe Analyzer enables rapid, nondestructive analyses of solid and liquid substances and formulations. With the NIRS XDS SmartProbe Analyzer, the identity and quality of a substance can be determined directly in the respective original transport containers, no matter whether it be bottles, bags or other containers. The design, which is just as robust as it is ergonomic, makes the NIRS XDS SmartProbe Analyzer the ideal quality control solution, both in the warehouse and in the laboratory. Using the NIRS XDS SmartProbe Analyzer could not be easier. The measurement is taken by holding the probe in the sample and pressing the measurement button. Pass/fail results can be read off on the handle immediately after the measurement.

Our family of portable Raman spectrometers with fiber-optically coupled sampling offer you versatility to interface with accessories optimized for your sample needs, allowing you to do more with less. Each system’s small footprint, lightweight design, and low power consumption helps to provide research grade Raman capabilities anywhere. We pride ourselves on providing you with portable Raman spectrometers that feature a unique blend of high resolution and field-portability.

The TacticID-GP Plus is a field-ready handheld Raman instrument designed for rapid, nondestructive chemical identification to reduce operational uncertainty and response time. Featuring an intuitive workflow and touchscreen, samples can be nondestructively analyzed through opaque and transparent packaging, with sample threat level displayed prominently for first responders, safety personnel, law enforcement, bomb squads, customs and border patrol, and hazmat teams to act quickly with minimal sample contact. The TacticID-GP Plus utilizes proven Raman spectroscopy, allowing users to get real-time actionable identification of samples with threat level and GHS and NFPA704 safety information clearly displayed.

The TacticID®–N Plus is a field-ready handheld instrument specifically designed for non-contact forensic analysis of narcotics, pharmaceutical drugs, cutting agents and precursors by law enforcement personnel. Featuring an intuitive workflow and touchscreen, samples can be nondestructively analyzed through opaque and transparent packaging, with sample threat level displayed prominently for first responders, safety personnel, law enforcement, bomb squads, customs and border patrol, and hazmat team to act quickly with minimal sample contact. The TacticID-N Plus utilizes laboratory-proven Raman spectroscopy, which allows users to obtain actionable identification of illicit substances without ever compromising the integrity of the sample or the chain of evidence.

The TacticID®-1064 is a field-ready handheld spectral analysis instrument designed for non-contact forensic analysis by safety personnel and first responders, including law enforcement personnel, bomb squads, customs and border patrol, hazmat technicians, and more. The TacticID-1064 utilizes proven Raman spectroscopy, allowing users to get real-time actionable identification of unknown chemicals, narcotics, pharmaceutical drugs, explosives* and many other substances in less than 1 minute, significantly reducing operational uncertainty and response time. By utilizing the 1064nm wavelength, the TacticID-1064 avoids fluorescence, allowing users to work with even tough street samples.

The LM20 contains an intensifier pump designed to supply the desired pressure at a constant rate to the product stream. As the pump travels through its pressure stroke, it drives the product at constant pressure through precisely defined fixed-geometry microchannels within the interaction chamber.

As a result, the product stream accelerates to high velocities, creating shear rates within the product stream that are orders of magnitude greater than any other conventional means. All of the product experiences identical processing conditions, producing the desired results, including: uniform particle and droplet size reduction (often submicron), deagglomeration and high-yield cell disruption.

The LV1 benchtop was developed as a result of customer demand to bring Microfluidizer quality nanotechnology processing to the milliliter scale with applications in the pharmaceutical, biotechnology, chemical, nutraceutical/food, cosmetic and energy industries:

• Academic and commercial sectors
• Drug discovery, Adme Tox, basic research and development
• Proteomics and genomics applications

Microfluidizer processors offer exclusive benefits due to the fixed-geometry interaction chamber and constant pressure pumping system. The unique technology enables customers to achieve smaller sample sizes than other methods with more uniform distribution and scaleup guaranteed.

With the LV1, researchers with limited resources and high value samples are able to enhance their wide variety of applications and materials with benefits only a Microfluidizer processor can provide:

• Stable nanoemulsions
• Highest protein recovery (typically >99% for E. coli after one pass)
• Challenging cell disruption (e.g. yeast, insect cells)
• Improved bioavailability
• Targeted delivery
• Nanoencapsulation (e.g. polymers, liposomes )
• Deagglomeration

As leading pharmaceutical companies continue to explore the benefits of continuous manufacturing and bottom-up nanoparticle creation, Microfluidics’ PureNano Continuous Crystallizer is being used to create stabile inhalable formulations, improve the bioavailability of antibiotics and target delivery of novel cancer treatments, among other possibilities.

Microfluidizer homogenizers combine superior results with easy handling and small footprint.

The series of air-driven homogenizers are lightweigh and easy-to-use and are suitable for batch and continuous flow processing, often used for emulsions, dispersions and liposomes in pharmaceutical, cosmetic and food and beverage applications. They feature in line cleaning, a pressure gauge, and a small footprint for bench use (or under hood).

Microfluidics LM10 Microfluidizer® High Pressure Lab Homogenizer is a unique solution to maintaining consistent process pressure, ensures 100% of your material gets exactly the same treatment.

The new LM10 Microfluidizer is a digitally controlled lab unit for small sample material processing. The LM10 converts pressure energy more efficiently into shear and impact forces, attaining targeted size reduction at lower peak pressure, which results in less sample temperature rise during processing.

The micro-channel architecture of each interaction chamber enables linear volumetric scale-up for larger capacity processing, guaranteeing process performance at pilot/production scales, and minimizing additional development time.

M-110EH-30 Electric-Hydraulic Laboratory Microfluidizer Processor for Continuous High Shear Fluid Processing. The M-110EH-30 has been designed to reliably achieve continuous operating pressures to 30,000 psi. The processor maximizes the energy-per-unit fluid volume, resulting in uniform submicron particle and droplet sizes. Utilizing Microfluidics’ fixed geometry diamond interaction chamber technology, nd a ceramic (Zirconia) plunger, the M-110EH-30 is capable of processing a wide variety of fluids such as simple oil-in-water emulsions, solids-in-liquid suspensions, and cell disruptions, including the most difficult yeasts and plant cells, in 1-2 passes. What’s more, the process is repeatable and is guaranteed to scaleup to pilot and/or production volumes.

High Pressure Laboratory Microfluidizer Processor for High-Shear Fluid Processing

M-110Y Microfluidizer processor is a lab machine that provides the highest shear rates of any competitive processing equipment on the market today, maximizing the energy-perunit fluid volume to produce uniform submicron particle and droplet sizes. Process pressures range from 206-1586 bar (3,000-23,000 psi), enabling the processing of a wide variety of products ranging from simple oilin-water emulsions to high-weightpercent solids in liquid suspensions, as well as low to high concentration cell disruption. The system is easy to operate and is designed for clean-inplace without disassembly.

Microfluidizer Processor for Continuous High Shear Fluid Processing in Industrial Environments. Microfluidics produces patented Microfluidizer processor equipment with high-pressure, fixed-geometry interaction chambers that impart high shear rates to product formulations. The M-700 generates up to 30,000 psi operating pressure (40,000 psi available as special option) for premium results at an affordable cost.

The MP350 Microlyser™ Processor is an innovation in high shear processing which utilizes a hybrid approach by incorporating Microfluidics proprietary Interaction Chamber™ technology with a unique electric pumping system, to deliver the highest cell disruption yields.

From E. coli to difficult yeast cells, the MP350 Microlyser™ can provide consistent pressure across the batch cycle to maximize protein yields and ensure high product quality in cell disruption of various cells. It has the same multi-slotted fixed-geometry Interaction Chamber™ that all Microfluidics equipment possess which provides consistent shear & uniform processing for reduced batch time & lesser passes.

The scale up to production volumes with the MP350 model is seamless & cost effective once the suitable cell disruption lab and pilot batches are achieved. Enquire with us today!

Microtrac MRB’s NANOTRAC Flex is a highly flexible nanoparticle size analyzer based on Dynamic Light Scattering (DLS) which provides information on particle size, concentration, and molecular weight. It allows faster measurements with reliable technology, higher precision, and better accuracy. All of this combined into compact a DLS analyzer with a revolutionary fixed optical probe.

With the unique and flexible probe design and the use of the Laser Amplified Detection method in the NANOTRAC FLEX, the user is able to choose an appropriate vessel as a measurement cell to satisfy the needs of any application. This design also allows measurements of samples over a wide concentration range, monomodal or multimodal samples, all without prior knowledge of the particle size distribution. This is made possible through the use of the Frequency Power Spectrum (FPS) method instead of classical Photon Correlation Spectroscopy (PCS).