SARTORIUS – Crossflow
Tangential Flow Filtration (TFF) Process Solutions
Spanning production capacity needs with maximum equipment utilization. Mitigate the risk of operator error and significantly reduce your development time in both single-use or hybrid processes. Our solutions provide high-performance from process development to commercial manufacturing in various upstream and downstream bioprocessing steps, including cell harvest, clarification, perfusion, ultrafiltration, and diafiltration.
Sartorius offers flexible tangential flow filtration (TFF) systems for process development and clinical trials, from laboratory environments up to commercial production batches. The TFF portfolio can flex to accommodate individual requirements, with a range of options that includes cost-efficient multi-use systems or closed systems with single-use flow kits for aseptic processing.
Key Features
• PD & Bench scale up to Pilot to Commercial scale
• Membrane area 10 cm² – 10 m²
• Ultrafiltration and Microfiltration cassettes
• Single use and Multiuse
Technical Specifications
| Model | Ambr® Crossflow | Sartoflow® Smart | Sartoflow® Advanced | Sartoflow® 150 | Sartoflow® Expert SU | Sartoflow® 1000 | Sartoflow® 4500 |
| Membrane Area | 10, 50 cm² | 50 cm² – 0.14 m² | 0.1 – 0.21 m² | 0.1 – 0.4 m² | 0.1 – 0.4, 1.4 m² | 0.6 – 2.8 m² | Up to 10 m² |
| Vessel Volume | 100 mL | 1 L with mixing | 10 L | 5, 10, 20 L | 20 L mixing | 10, 20, 100 L | |
| Flow Rate / Pump Capacity | 0 – 80 mL/min | 1 – 100 L/h | 700 L/h | 5 – 150 L/h | 900L/h | 20 – 1,000 L/h | 00 – 4500 L/h |
| Minimum Recirculation Volume | 5 mL | < 20 mL | ~ 170 mL | 130 mL | ~ 600 mL | ~ 1.2 L | Depends on bag size |
| Automation Level | Fully | Semi | Fully | Fully | Fully | Fully | |
| Process Mode (multi/single) | Multi-use or single-use | Multi-use | Multi-use | Single-use | Single-use | Single-use |
Sartorius – Sartoflow® 150
Sartorius – Sartoflow® Expert SU
Sartorius – Sartoflow® 1000
Sartorius – Sartoflow® 4500
Key Industries
- Pharmaceutical
- Food & Beverage
Brand
The Sartorius Group is a leading international partner of the biopharmaceutical industry and the research sector. We are helping biotech scientists and engineers across the entire globe to develop and manufacture medications from the first idea to production. So more people will have access to better medicine.
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